# Single and Multiple Ascending Dose Study to Evaluate AMG 786 in Healthy Participants and Participants With Obesity

> **NCT05406115** · PHASE1 · COMPLETED · sponsor: **Amgen** · enrollment: 65 (actual)

## Conditions studied

- Obesity

## Interventions

- **DRUG:** AMG 786
- **OTHER:** Placebo

## Key facts

- **NCT ID:** NCT05406115
- **Lead sponsor:** Amgen
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-07-26
- **Primary completion:** 2023-08-21
- **Final completion:** 2023-08-21
- **Target enrollment:** 65 (ACTUAL)
- **Last updated:** 2025-10-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05406115

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05406115, "Single and Multiple Ascending Dose Study to Evaluate AMG 786 in Healthy Participants and Participants With Obesity". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05406115. Licensed CC0.

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