# Mechanisms of Palmitoylethanolamide (PEA) to Alter Pain Sensitivity in Knee Osteoarthritis

> **NCT05406726** · NA · COMPLETED · sponsor: **University of Maryland, Baltimore** · enrollment: 13 (actual)

## Conditions studied

- Osteoarthritis, Knee

## Interventions

- **DIETARY_SUPPLEMENT:** palmitoylethanolamide
- **DIETARY_SUPPLEMENT:** Placebo

## Key facts

- **NCT ID:** NCT05406726
- **Lead sponsor:** University of Maryland, Baltimore
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2023-03-22
- **Primary completion:** 2024-01-02
- **Final completion:** 2024-01-02
- **Target enrollment:** 13 (ACTUAL)
- **Last updated:** 2024-11-05


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05406726

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05406726, "Mechanisms of Palmitoylethanolamide (PEA) to Alter Pain Sensitivity in Knee Osteoarthritis". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT05406726. Licensed CC0.

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