# A Study Evaluating the Safety and Efficacy of Hormone Replacement Therapy With ST-1891 Compared to Levothyroxine in Patients With Primary Hypothyroidism

> **NCT05412979** · PHASE2 · COMPLETED · sponsor: **Sention Therapeutics, LLC** · enrollment: 490 (actual)

## Conditions studied

- Hypothyroidism

## Interventions

- **DRUG:** ST-1891
- **DRUG:** Levothyroxine

## Key facts

- **NCT ID:** NCT05412979
- **Lead sponsor:** Sention Therapeutics, LLC
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-04-29
- **Primary completion:** 2023-10-04
- **Final completion:** 2023-10-04
- **Target enrollment:** 490 (ACTUAL)
- **Last updated:** 2024-08-26


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05412979

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05412979, "A Study Evaluating the Safety and Efficacy of Hormone Replacement Therapy With ST-1891 Compared to Levothyroxine in Patients With Primary Hypothyroidism". Retrieved via AI Analytics 2026-06-16 from https://api.ai-analytics.org/clinical/NCT05412979. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*