# Effect of an Investigational Lozenge (Biofresh® 4plus) Versus Placebo Control on Oral Malodor (Intra-Oral Halitosis)

> **NCT05413382** · NA · COMPLETED · sponsor: **Novozymes A/S** · enrollment: 53 (actual)

## Conditions studied

- Halitosis

## Interventions

- **DIETARY_SUPPLEMENT:** Biofresh® 4plus
- **DIETARY_SUPPLEMENT:** Placebo

## Key facts

- **NCT ID:** NCT05413382
- **Lead sponsor:** Novozymes A/S
- **Sponsor class:** INDUSTRY
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-09-28
- **Primary completion:** 2021-11-04
- **Final completion:** 2021-12-22
- **Target enrollment:** 53 (ACTUAL)
- **Last updated:** 2022-06-10


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05413382

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05413382, "Effect of an Investigational Lozenge (Biofresh® 4plus) Versus Placebo Control on Oral Malodor (Intra-Oral Halitosis)". Retrieved via AI Analytics 2026-06-23 from https://api.ai-analytics.org/clinical/NCT05413382. Licensed CC0.

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