# Impacts of Mechanistic Target of Rapamycin (mTOR) Inhibition on Aged Human Muscle (Rapamune)

> **NCT05414292** · NA · RECRUITING · sponsor: **University of Nottingham** · enrollment: 16 (estimated)

## Conditions studied

- Muscle Atrophy
- Age-Related Sarcopenia

## Interventions

- **DRUG:** Rapamune (sirolimus) 1Mg Tablet
- **BEHAVIORAL:** Unilateral resistance exercise training

## Key facts

- **NCT ID:** NCT05414292
- **Lead sponsor:** University of Nottingham
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2021-08-06
- **Primary completion:** 2027-05-01
- **Final completion:** 2027-05-01
- **Target enrollment:** 16 (ESTIMATED)
- **Last updated:** 2025-04-10

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05414292

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05414292, "Impacts of Mechanistic Target of Rapamycin (mTOR) Inhibition on Aged Human Muscle (Rapamune)". Retrieved via AI Analytics 2026-07-13 from https://api.ai-analytics.org/clinical/NCT05414292. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*