# DUET Study: A Clinical Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of Orally Administered TERN-501 as Monotherapy and in Combination With TERN-101 in Noncirrhotic Adults With Presumed Non-Alcoholic Steatohepatitis

> **NCT05415722** · PHASE2 · COMPLETED · sponsor: **Terns, Inc.** · enrollment: 162 (actual)

## Conditions studied

- NASH - Nonalcoholic Steatohepatitis

## Interventions

- **DRUG:** TERN-501
- **DRUG:** TERN-101
- **OTHER:** Placebo

## Key facts

- **NCT ID:** NCT05415722
- **Lead sponsor:** Terns, Inc.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-06-28
- **Primary completion:** 2023-07-10
- **Final completion:** 2023-07-10
- **Target enrollment:** 162 (ACTUAL)
- **Last updated:** 2025-03-12


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05415722

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05415722, "DUET Study: A Clinical Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of Orally Administered TERN-501 as Monotherapy and in Combination With TERN-101 in Noncirrhotic Adults With Presumed Non-Alcoholic Steatohepatitis". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT05415722. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*