# iCLAS™ Cryoablation System Post-Market Clinical Follow-up (PMCF) Study

> **NCT05416086** · NA · TERMINATED · sponsor: **Adagio Medical** · enrollment: 91 (actual)

## Conditions studied

- Atrial Fibrillation
- Atrial Flutter
- Paroxysmal Atrial Fibrillation
- Persistent Atrial Fibrillation

## Interventions

- **DEVICE:** cryoablation procedure using the iCLAS Cryoablation System

## Key facts

- **NCT ID:** NCT05416086
- **Lead sponsor:** Adagio Medical
- **Sponsor class:** INDUSTRY
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2021-09-03
- **Primary completion:** 2025-01-28
- **Final completion:** 2025-01-28
- **Target enrollment:** 91 (ACTUAL)
- **Why stopped:** Adagio Medical no longer manufactures the iCLAS Cryoablation System
- **Last updated:** 2026-04-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05416086

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05416086, "iCLAS™ Cryoablation System Post-Market Clinical Follow-up (PMCF) Study". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT05416086. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*