# A Randomized Trial of Five Fraction Partial Breast Irradiation (RAPID2)

> **NCT05417516** · PHASE3 · RECRUITING · sponsor: **Ontario Clinical Oncology Group (OCOG)** · enrollment: 910 (estimated)

## Conditions studied

- Breast Neoplasm Female
- Radiotherapy
- Cosmetic Outcome

## Interventions

- **RADIATION:** Whole Breast Irradiation (WBI)
- **RADIATION:** Partial Breast Irradiation (PBI)

## Key facts

- **NCT ID:** NCT05417516
- **Lead sponsor:** Ontario Clinical Oncology Group (OCOG)
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-11-20
- **Primary completion:** 2029-11
- **Final completion:** 2031-11
- **Target enrollment:** 910 (ESTIMATED)
- **Last updated:** 2026-04-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05417516

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05417516, "A Randomized Trial of Five Fraction Partial Breast Irradiation (RAPID2)". Retrieved via AI Analytics 2026-06-09 from https://api.ai-analytics.org/clinical/NCT05417516. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*