# Improving Vaccination in Older Adults by Inducing Autophagy With Spermidine

> **NCT05421546** · NA · COMPLETED · sponsor: **University of Oxford** · enrollment: 40 (actual)

## Conditions studied

- COVID-19
- Vaccine Reaction

## Interventions

- **DIETARY_SUPPLEMENT:** Spermidine or Placebo

## Key facts

- **NCT ID:** NCT05421546
- **Lead sponsor:** University of Oxford
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-08-01
- **Primary completion:** 2023-08-31
- **Final completion:** 2023-12-02
- **Target enrollment:** 40 (ACTUAL)
- **Last updated:** 2024-05-09


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05421546

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05421546, "Improving Vaccination in Older Adults by Inducing Autophagy With Spermidine". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT05421546. Licensed CC0.

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