# Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial

> **NCT05421741** · PHASE4 · RECRUITING · sponsor: **Wake Forest University Health Sciences** · enrollment: 484 (estimated)

## Conditions studied

- Osteomyelitis Tibia
- Tibial Fractures
- Open Tibia Fracture

## Interventions

- **DRUG:** Antibiotic coated intramedullary Nail
- **OTHER:** Standard Intramedullary Nail

## Key facts

- **NCT ID:** NCT05421741
- **Lead sponsor:** Wake Forest University Health Sciences
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-05-15
- **Primary completion:** 2026-12
- **Final completion:** 2027-12
- **Target enrollment:** 484 (ESTIMATED)
- **Last updated:** 2026-03-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05421741

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05421741, "Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial". Retrieved via AI Analytics 2026-07-20 from https://api.ai-analytics.org/clinical/NCT05421741. Licensed CC0.

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