# RESPONDER-HF Trial

> **NCT05425459** · NA · ACTIVE_NOT_RECRUITING · sponsor: **Corvia Medical** · enrollment: 750 (estimated)

## Conditions studied

- Heart Failure
- Heart Failure, Diastolic

## Interventions

- **DEVICE:** Corvia Atrial Shunt System / IASD System II
- **OTHER:** Intra-cardiac echocardiography (ICE), or transesophageal echocardiography (TEE)

## Key facts

- **NCT ID:** NCT05425459
- **Lead sponsor:** Corvia Medical
- **Sponsor class:** INDUSTRY
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2022-11-17
- **Primary completion:** 2027-07
- **Final completion:** 2031-03
- **Target enrollment:** 750 (ESTIMATED)
- **Last updated:** 2026-03-18


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05425459

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05425459, "RESPONDER-HF Trial". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT05425459. Licensed CC0.

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