# Bismuth-containing Quadruple Therapy for Helicobacter Pylori First-line Treatment of Different Tetracycline Doses

> **NCT05431075** · PHASE4 · COMPLETED · sponsor: **Shandong University** · enrollment: 406 (actual)

## Conditions studied

- Helicobacter Pylori Infection

## Interventions

- **DRUG:** Amoxicillin
- **DRUG:** Tetracycline tid
- **DRUG:** Tetracycline qid
- **DRUG:** Bismuth Potassium Citrate
- **DRUG:** Colloidal Bismuth Pectin
- **DRUG:** Esomeprazole 20mg

## Key facts

- **NCT ID:** NCT05431075
- **Lead sponsor:** Shandong University
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-07-01
- **Primary completion:** 2024-02-01
- **Final completion:** 2024-02-01
- **Target enrollment:** 406 (ACTUAL)
- **Last updated:** 2024-03-27

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05431075

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05431075, "Bismuth-containing Quadruple Therapy for Helicobacter Pylori First-line Treatment of Different Tetracycline Doses". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT05431075. Licensed CC0.

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