# A Two-blinded, Multicentre, Phase II/III RCT of Concurrent Chemo-radiotherapy Combined or Not Combined With TNF as the Therapy for LA-NPC

> **NCT05433597** · PHASE2,PHASE3 · NOT_YET_RECRUITING · sponsor: **Sun Yat-sen University** · enrollment: 172 (estimated)

## Conditions studied

- Nasopharyngeal Carcinoma
- TNF
- Chemo-radiotherapy

## Interventions

- **DRUG:** 5-fu
- **DRUG:** Cisplatin
- **RADIATION:** Radiotherapy
- **DRUG:** TNF
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT05433597
- **Lead sponsor:** Sun Yat-sen University
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2022-07-01
- **Primary completion:** 2024-07-01
- **Final completion:** 2029-07-01
- **Target enrollment:** 172 (ESTIMATED)
- **Last updated:** 2022-06-27

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05433597

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05433597, "A Two-blinded, Multicentre, Phase II/III RCT of Concurrent Chemo-radiotherapy Combined or Not Combined With TNF as the Therapy for LA-NPC". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT05433597. Licensed CC0.

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