# Effect of Supplemental Hydrocortisone During Stress in Prednisolone-induced Adrenal Insufficiency

> **NCT05435781** · PHASE4 · RECRUITING · sponsor: **Marianne Christina Klose** · enrollment: 250 (estimated)

## Conditions studied

- Adrenal Insufficiency
- Polymyalgia Rheumatica
- Giant Cell Arteritis

## Interventions

- **DRUG:** Hydrocortisone
- **DRUG:** Placebo for hydrocortisone

## Key facts

- **NCT ID:** NCT05435781
- **Lead sponsor:** Marianne Christina Klose
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2022-06-07
- **Primary completion:** 2026-06-30
- **Final completion:** 2028-03-01
- **Target enrollment:** 250 (ESTIMATED)
- **Last updated:** 2026-03-16

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05435781

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05435781, "Effect of Supplemental Hydrocortisone During Stress in Prednisolone-induced Adrenal Insufficiency". Retrieved via AI Analytics 2026-06-04 from https://api.ai-analytics.org/clinical/NCT05435781. Licensed CC0.

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