# G-CSF+DAC+BUCY vs G-CSF+DAC+BF Conditioning Regimen for Secondary Acute Myeloid Leukemia Undergoing Allo-HSCT

> **NCT05449899** · PHASE2,PHASE3 · UNKNOWN · sponsor: **Nanfang Hospital, Southern Medical University** · enrollment: 232 (estimated)

## Conditions studied

- Secondary Acute Myeloid Leukemia Evolving From MDS
- Allogeneic Hematopoietic Stem Cell Transplantation
- Conditioning

## Interventions

- **DRUG:** Granulocyte Colony-Stimulating Factor(G-CSF)
- **DRUG:** Decitabine (DAC)
- **DRUG:** Busulfan (BU)
- **DRUG:** Fludarabine (FLU)
- **DRUG:** Cyclophosphamide (CY)

## Key facts

- **NCT ID:** NCT05449899
- **Lead sponsor:** Nanfang Hospital, Southern Medical University
- **Sponsor class:** OTHER
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2022-07
- **Primary completion:** 2023-12
- **Final completion:** 2024-12
- **Target enrollment:** 232 (ESTIMATED)
- **Last updated:** 2022-07-08

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05449899

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05449899, "G-CSF+DAC+BUCY vs G-CSF+DAC+BF Conditioning Regimen for Secondary Acute Myeloid Leukemia Undergoing Allo-HSCT". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05449899. Licensed CC0.

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