# Physiological-based Pharmacokinetics Approach to Medication Exposure During Pregnancy and Breastfeeding

> **NCT05450978** · — · RECRUITING · sponsor: **University of Pittsburgh** · enrollment: 60 (estimated)

## Conditions studied

- Epilepsy
- Pregnancy Related

## Interventions

- **DRUG:** Lamotrigine
- **DRUG:** Levetiracetam
- **DRUG:** Oxcarbazepine

## Key facts

- **NCT ID:** NCT05450978
- **Lead sponsor:** University of Pittsburgh
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2022-07-20
- **Primary completion:** 2027-04-01
- **Final completion:** 2028-04-01
- **Target enrollment:** 60 (ESTIMATED)
- **Last updated:** 2026-05-06

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05450978

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05450978, "Physiological-based Pharmacokinetics Approach to Medication Exposure During Pregnancy and Breastfeeding". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05450978. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*