# Vaginal Estradiol Use in Pessary Care

> **NCT05458375** · EARLY_PHASE1 · TERMINATED · sponsor: **University of South Florida** · enrollment: 11 (actual)

## Conditions studied

- Pelvic Organ Prolapse
- Urinary Incontinence
- Pessary Ulcer of Vagina
- Vaginal Atrophy

## Interventions

- **DRUG:** Estradiol vaginal cream

## Key facts

- **NCT ID:** NCT05458375
- **Lead sponsor:** University of South Florida
- **Sponsor class:** OTHER
- **Phase:** EARLY_PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2022-12-29
- **Primary completion:** 2023-04-26
- **Final completion:** 2023-04-26
- **Target enrollment:** 11 (ACTUAL)
- **Why stopped:** There is a lack of potential study participants at our study site that would meet inclusion criteria, therefore, the study is not feasible and is being terminated.
- **Last updated:** 2023-05-11


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05458375

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05458375, "Vaginal Estradiol Use in Pessary Care". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT05458375. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*