# A Randomised, Cross-Over, Nicotine Pharmacokinetic and Pharmacodynamic Study of Heated Tobacco Products Compared to Combustible Cigarettes

> **NCT05459857** · NA · COMPLETED · sponsor: **Imperial Brands PLC** · enrollment: 24 (actual)

## Conditions studied

- Healthy Volunteers

## Interventions

- **OTHER:** Product A
- **OTHER:** Product B
- **OTHER:** Product C
- **OTHER:** Product D

## Key facts

- **NCT ID:** NCT05459857
- **Lead sponsor:** Imperial Brands PLC
- **Sponsor class:** INDUSTRY
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2021-10-01
- **Primary completion:** 2021-11-30
- **Final completion:** 2021-11-30
- **Target enrollment:** 24 (ACTUAL)
- **Last updated:** 2025-02-03


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05459857

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05459857, "A Randomised, Cross-Over, Nicotine Pharmacokinetic and Pharmacodynamic Study of Heated Tobacco Products Compared to Combustible Cigarettes". Retrieved via AI Analytics 2026-06-26 from https://api.ai-analytics.org/clinical/NCT05459857. Licensed CC0.

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