# Single and Multiple Intravenous Administrations of Estetrol (E4) in Healthy Adult Volunteers

> **NCT05460065** · PHASE1 · TERMINATED · sponsor: **NEURALIS s.a.** · enrollment: 8 (actual)

## Conditions studied

- Safety
- Pharmacokinetics

## Interventions

- **DRUG:** single E4 28.3 mg
- **DRUG:** single E4 94.4 mg
- **DRUG:** multiple E4 94.4 mg
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT05460065
- **Lead sponsor:** NEURALIS s.a.
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE1
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2022-04-19
- **Primary completion:** 2022-09-13
- **Final completion:** 2022-09-13
- **Target enrollment:** 8 (ACTUAL)
- **Why stopped:** Business decision by Sponsor.
- **Last updated:** 2025-07-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05460065

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05460065, "Single and Multiple Intravenous Administrations of Estetrol (E4) in Healthy Adult Volunteers". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT05460065. Licensed CC0.

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