# Pregabalin for Central Sensitization in TKA

> **NCT05460871** · PHASE4 · TERMINATED · sponsor: **University of Iowa** · enrollment: 20 (actual)

## Conditions studied

- Osteo Arthritis Knee
- Central Nervous System Sensitization

## Interventions

- **DRUG:** Pregabalin 75mg

## Key facts

- **NCT ID:** NCT05460871
- **Lead sponsor:** University of Iowa
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2023-02-21
- **Primary completion:** 2024-01-25
- **Final completion:** 2024-01-25
- **Target enrollment:** 20 (ACTUAL)
- **Why stopped:** Enrollment lower than anticipated; none of the subjects completing the study.
- **Last updated:** 2025-03-04


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05460871

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05460871, "Pregabalin for Central Sensitization in TKA". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT05460871. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*