# Project 1 Aim 2, Adaptations of the Brain in Chronic Pain With Opioid Exposure

> **NCT05463367** · PHASE2 · ACTIVE_NOT_RECRUITING · sponsor: **Northwestern University** · enrollment: 60 (actual)

## Conditions studied

- Opioid Use
- Opioid Dependence
- Opioid-use Disorder
- Narcotic Use
- Back Pain
- Back Injuries
- Chronic Pain
- Chronic Low-back Pain
- Pain, Chronic
- Pain;Back Low;Chronic
- Pain, Back

## Interventions

- **DRUG:** Carbidopa-Levodopa 25 Mg-100 Mg Oral Tablet
- **DRUG:** Naproxen 500 Mg
- **DRUG:** Opioids

## Key facts

- **NCT ID:** NCT05463367
- **Lead sponsor:** Northwestern University
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2021-01-01
- **Primary completion:** 2025-06-01
- **Final completion:** 2025-06-01
- **Target enrollment:** 60 (ACTUAL)
- **Last updated:** 2024-11-27

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05463367

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05463367, "Project 1 Aim 2, Adaptations of the Brain in Chronic Pain With Opioid Exposure". Retrieved via AI Analytics 2026-05-28 from https://api.ai-analytics.org/clinical/NCT05463367. Licensed CC0.

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