Sacubitril/Valsartan in PriMAry preventIoN of the Cardiotoxicity of Systematic breaST canceR trEAtMent (MAINSTREAM)

NCT05465031 · clinicaltrials.gov ↗

PHASE4

Phase

RECRUITING

Status

600

Enrollment

OTHER

Sponsor class

Conditions

Breast Cancer
Neoplasm, Breast
Breast Diseases
Antihypertensive Agents
Sacubitril/Valsartan
Angiotensin II Type 1 Receptor Blockers
Angiotensin Receptor Antagonists
Molecular Mechanisms of Pharmacological Action
Heart Failure
Cardiac Toxicity
Cancer, Therapy-Related
Cancer Therapy-Related Cardiac Dysfunction
Cardiotoxicity

Interventions

DRUG: Sacubitril-valsartan
DRUG: Placebo

Sponsor

Silesian Centre for Heart Diseases

Collaborators

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