# CREST-2 Long-term Observational Extension Study

> **NCT05465122** · — · ENROLLING_BY_INVITATION · sponsor: **Mayo Clinic** · enrollment: 2480 (estimated)

## Conditions studied

- Stenoses, Carotid

## Interventions

- **PROCEDURE:** Carotid Endarterectomy
- **PROCEDURE:** FDA-approved carotid stents
- **OTHER:** Intensive Medical Management

## Key facts

- **NCT ID:** NCT05465122
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** ENROLLING_BY_INVITATION
- **Start date:** 2022-07-05
- **Primary completion:** 2026-02-28
- **Final completion:** 2026-02-28
- **Target enrollment:** 2480 (ESTIMATED)
- **Last updated:** 2025-09-05

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05465122

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05465122, "CREST-2 Long-term Observational Extension Study". Retrieved via AI Analytics 2026-07-20 from https://api.ai-analytics.org/clinical/NCT05465122. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*