# Effect of Tofogliflozin on UACR Compared to Metformin Hydrochloride in Diabetic Kidney Disease (TRUTH-DKD)

> **NCT05469659** · PHASE2 · RECRUITING · sponsor: **Shinshu University** · enrollment: 120 (estimated)

## Conditions studied

- T2DM (Type 2 Diabetes Mellitus)
- Metformin
- SGLT2-Inhibitors

## Interventions

- **DRUG:** Tofogliflozin
- **DRUG:** Metformin

## Key facts

- **NCT ID:** NCT05469659
- **Lead sponsor:** Shinshu University
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2021-09-22
- **Primary completion:** 2025-10-30
- **Final completion:** 2026-10-30
- **Target enrollment:** 120 (ESTIMATED)
- **Last updated:** 2022-07-22

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05469659

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05469659, "Effect of Tofogliflozin on UACR Compared to Metformin Hydrochloride in Diabetic Kidney Disease (TRUTH-DKD)". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT05469659. Licensed CC0.

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