# A Study to Learn About New COVID-19 RNA Vaccine Candidates in COVID-19 Vaccine-Experienced Healthy Individuals

> **NCT05472038** · PHASE2,PHASE3 · COMPLETED · sponsor: **BioNTech SE** · enrollment: 1453 (actual)

## Conditions studied

- SARS-CoV-2 Infection
- COVID-19

## Interventions

- **BIOLOGICAL:** BNT162b5 Bivalent (WT/OMI BA.2)
- **BIOLOGICAL:** BNT162b2 Bivalent (WT/OMI BA.1)
- **BIOLOGICAL:** BNT162b2 Bivalent (WT/OMI BA.4/BA.5)
- **BIOLOGICAL:** BNT162b5 Bivalent (Original/OMI BA.4/BA.5)
- **BIOLOGICAL:** BNT162b6 Bivalent (Original/OMI BA.4/BA.5)
- **BIOLOGICAL:** BNT162b7 Bivalent (Original/OMI BA.4/BA.5)
- **BIOLOGICAL:** BNT162b7 Monovalent (OMI BA.4/BA.5)

## Key facts

- **NCT ID:** NCT05472038
- **Lead sponsor:** BioNTech SE
- **Sponsor class:** INDUSTRY
- **Phase:** PHASE2,PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-07-26
- **Primary completion:** 2024-03-26
- **Final completion:** 2024-03-26
- **Target enrollment:** 1453 (ACTUAL)
- **Last updated:** 2025-10-01

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05472038

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05472038, "A Study to Learn About New COVID-19 RNA Vaccine Candidates in COVID-19 Vaccine-Experienced Healthy Individuals". Retrieved via AI Analytics 2026-08-24 from https://api.ai-analytics.org/clinical/NCT05472038. Licensed CC0.

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