Alpelisib in Combination With Carboplatin in Patients With Solid Tumors and HPV-Positive Squamous Cell Carcinoma

NCT05472220 · clinicaltrials.gov ↗

PHASE1

Phase

WITHDRAWN

Status

OTHER

Sponsor class

Stopped Sponsor funding

Conditions

Solid Tumors, Adult
PIK3CA Mutation-Related Tumors
PIK3CA Mutation
Human Papillomavirus-Related Carcinoma
HPV-Related Squamous Cell Carcinoma
Human Papillomavirus-Related Squamous Cell Carcinoma
Locally Advanced Malignant Solid Neoplasm
Metastatic Malignant Solid Neoplasm

Interventions

DRUG: Alpelisib
DRUG: Carboplatin
DRUG: Hyperpolarized Carbon-13 (13C) Pyruvate
DEVICE: Continuous Glucose Monitor (CGM)

Sponsor

Pamela Munster

Collaborators

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