# Periurethral vs Intravaginal Estrogen for Prevention of Recurrent Urinary Tract Infections

> **NCT05472779** · PHASE2 · COMPLETED · sponsor: **Stephanie Wang Zuo** · enrollment: 114 (actual)

## Conditions studied

- Recurrent Urinary Tract Infection

## Interventions

- **DRUG:** Periurethral application of estradiol cream
- **DRUG:** Intravaginal application of estradiol cream

## Key facts

- **NCT ID:** NCT05472779
- **Lead sponsor:** Stephanie Wang Zuo
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2023-01-03
- **Primary completion:** 2025-06-15
- **Final completion:** 2025-06-25
- **Target enrollment:** 114 (ACTUAL)
- **Last updated:** 2025-07-08


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05472779

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05472779, "Periurethral vs Intravaginal Estrogen for Prevention of Recurrent Urinary Tract Infections". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT05472779. Licensed CC0.

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