# TIzanidine for the Preventive Treatment of Episodic MigrainE （TIME）

> **NCT05484349** · PHASE3 · RECRUITING · sponsor: **Second Affiliated Hospital, School of Medicine, Zhejiang University** · enrollment: 189 (estimated)

## Conditions studied

- Migraine Without Aura
- Migraine With Aura

## Interventions

- **DRUG:** Tizanidine Hydrochloride
- **DRUG:** Tizanidine Hydrochloride
- **DRUG:** Tizanidine Hydrochloride Placebo

## Key facts

- **NCT ID:** NCT05484349
- **Lead sponsor:** Second Affiliated Hospital, School of Medicine, Zhejiang University
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-06-01
- **Primary completion:** 2025-12-25
- **Final completion:** 2025-12-25
- **Target enrollment:** 189 (ESTIMATED)
- **Last updated:** 2024-08-01

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05484349

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05484349, "TIzanidine for the Preventive Treatment of Episodic MigrainE （TIME）". Retrieved via AI Analytics 2026-06-01 from https://api.ai-analytics.org/clinical/NCT05484349. Licensed CC0.

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