# Prospective, Randomized, Open Label Controlled Trial To Evaluate The Safety And Efficacy Of Dexmedetomidine Use Beyond 24 Hours Compared With Midazolam In Children Admitted To Pediatric Intensive Care Unit at King Abdullah Specialist Children Hospital- Ministry of National Guard Health Affairs.

> **NCT05485519** · PHASE3 · UNKNOWN · sponsor: **King Abdullah International Medical Research Center** · enrollment: 430 (estimated)

## Conditions studied

- Dexmedetomidine
- Midazolam
- Withdrawal Symptoms
- Failure of Extubation

## Interventions

- **DRUG:** Dexmedetomidine
- **DRUG:** Midazolam

## Key facts

- **NCT ID:** NCT05485519
- **Lead sponsor:** King Abdullah International Medical Research Center
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2022-04-21
- **Primary completion:** 2024-05
- **Final completion:** 2024-05
- **Target enrollment:** 430 (ESTIMATED)
- **Last updated:** 2023-04-27


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05485519

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05485519, "Prospective, Randomized, Open Label Controlled Trial To Evaluate The Safety And Efficacy Of Dexmedetomidine Use Beyond 24 Hours Compared With Midazolam In Children Admitted To Pediatric Intensive Care Unit at King Abdullah Specialist Children Hospital- Ministry of National Guard Health Affairs.". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT05485519. Licensed CC0.

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