# Pulmonary REsistance Modification Under Treatment With Sacubitril/valsartaN in paTients With Heart Failure With Reduced Ejection Fraction

> **NCT05487261** · PHASE4 · UNKNOWN · sponsor: **Clinical Hospital Heliodor Swiecicki of the Medical University of Karol Marcinkowski in Poznań** · enrollment: 260 (estimated)

## Conditions studied

- Heart Failure

## Interventions

- **DRUG:** Sacubitril-valsartan
- **DRUG:** Enalapril
- **DRUG:** placebo
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT05487261
- **Lead sponsor:** Clinical Hospital Heliodor Swiecicki of the Medical University of Karol Marcinkowski in Poznań
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2022-12-13
- **Primary completion:** 2025-02
- **Final completion:** 2025-11
- **Target enrollment:** 260 (ESTIMATED)
- **Last updated:** 2023-06-18

## Collaborators

- [object Object]
- [object Object]
- [object Object]
- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05487261

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05487261, "Pulmonary REsistance Modification Under Treatment With Sacubitril/valsartaN in paTients With Heart Failure With Reduced Ejection Fraction". Retrieved via AI Analytics 2026-05-29 from https://api.ai-analytics.org/clinical/NCT05487261. Licensed CC0.

---

*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*