# Anhedonia, Development, and Emotions: Phenotyping and Therapeutics

> **NCT05487885** · PHASE4 · COMPLETED · sponsor: **Erika Forbes** · enrollment: 123 (actual)

## Conditions studied

- Depression
- Anhedonia

## Interventions

- **DEVICE:** Continuous theta burst stimulation (cTBS)
- **BEHAVIORAL:** Positive Affect Training
- **DRUG:** Ketamine Injectable Solution

## Key facts

- **NCT ID:** NCT05487885
- **Lead sponsor:** Erika Forbes
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-07-22
- **Primary completion:** 2024-12-19
- **Final completion:** 2025-06-01
- **Target enrollment:** 123 (ACTUAL)
- **Last updated:** 2026-03-17


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05487885

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05487885, "Anhedonia, Development, and Emotions: Phenotyping and Therapeutics". Retrieved via AI Analytics 2026-05-26 from https://api.ai-analytics.org/clinical/NCT05487885. Licensed CC0.

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