# Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers

> **NCT05489549** · — · RECRUITING · sponsor: **University of Texas Southwestern Medical Center** · enrollment: 500 (estimated)

## Conditions studied

- Amyloidosis, Hereditary
- Amyloidosis Cardiac
- Amyloidosis, Familial
- Transthyretin-Related (ATTR) Familial Amyloid Cardiomyopathy
- Transthyretin Gene Mutation

## Interventions

_None listed._

## Key facts

- **NCT ID:** NCT05489549
- **Lead sponsor:** University of Texas Southwestern Medical Center
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** RECRUITING
- **Start date:** 2022-11-21
- **Primary completion:** 2027-06-30
- **Final completion:** 2027-06-30
- **Target enrollment:** 500 (ESTIMATED)
- **Last updated:** 2025-06-04

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05489549

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05489549, "Subclinical Transthyretin Cardiac Amyloidosis in V122I TTR Carriers". Retrieved via AI Analytics 2026-05-29 from https://api.ai-analytics.org/clinical/NCT05489549. Licensed CC0.

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