# Cytokine Guided Risk Stratification and Treatment in Pediatric Hemophagocytic Lymphohistiocytosis

> **NCT05491304** · PHASE4 · UNKNOWN · sponsor: **The Children's Hospital of Zhejiang University School of Medicine** · enrollment: 400 (estimated)

## Conditions studied

- Hemophagocytic Lymphohistiocytoses
- Cytokine Storm

## Interventions

- **DRUG:** Dexamethasone
- **DRUG:** Etoposide
- **DRUG:** Ruxolitinib

## Key facts

- **NCT ID:** NCT05491304
- **Lead sponsor:** The Children's Hospital of Zhejiang University School of Medicine
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2022-09-01
- **Primary completion:** 2024-12-31
- **Final completion:** 2025-12-31
- **Target enrollment:** 400 (ESTIMATED)
- **Last updated:** 2022-10-06

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05491304

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05491304, "Cytokine Guided Risk Stratification and Treatment in Pediatric Hemophagocytic Lymphohistiocytosis". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05491304. Licensed CC0.

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