# An Observational Study to Assess Change in Disease Activity and Adverse Events of Upadacitinib in Adult Participants With Moderate to Severe Ulcerative Colitis (UC) in Real-World Practice

> **NCT05494606** · — · ACTIVE_NOT_RECRUITING · sponsor: **AbbVie** · enrollment: 785 (actual)

## Conditions studied

- Ulcerative Colitis

## Interventions

_None listed._

## Key facts

- **NCT ID:** NCT05494606
- **Lead sponsor:** AbbVie
- **Sponsor class:** INDUSTRY
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2022-08-15
- **Primary completion:** 2028-03
- **Final completion:** 2028-03
- **Target enrollment:** 785 (ACTUAL)
- **Last updated:** 2025-02-28


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05494606

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05494606, "An Observational Study to Assess Change in Disease Activity and Adverse Events of Upadacitinib in Adult Participants With Moderate to Severe Ulcerative Colitis (UC) in Real-World Practice". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT05494606. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*