# Exparel Use in Peripheral Nerve Blocks and Local Infiltration for Foot and Ankle Surgery

> **NCT05494645** · PHASE4 · COMPLETED · sponsor: **St. Luke's Hospital, Pennsylvania** · enrollment: 248 (actual)

## Conditions studied

- Pain, Postoperative
- Pain, Acute Postoperative
- Ankle Fractures
- Ankle Injuries and Disorders

## Interventions

- **DRUG:** Exparel
- **DRUG:** Peripheral Nerve Block

## Key facts

- **NCT ID:** NCT05494645
- **Lead sponsor:** St. Luke's Hospital, Pennsylvania
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** COMPLETED
- **Start date:** 2022-03-01
- **Primary completion:** 2023-01-31
- **Final completion:** 2023-01-31
- **Target enrollment:** 248 (ACTUAL)
- **Last updated:** 2026-04-28


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05494645

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05494645, "Exparel Use in Peripheral Nerve Blocks and Local Infiltration for Foot and Ankle Surgery". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05494645. Licensed CC0.

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