# A Study to Give Treatment Inside the Eye to Treat Retinoblastoma

> **NCT05504291** · PHASE2 · RECRUITING · sponsor: **Children's Oncology Group** · enrollment: 26 (estimated)

## Conditions studied

- Bilateral Retinoblastoma
- Childhood Intraocular Retinoblastoma
- Group D Retinoblastoma
- Stage I Retinoblastoma
- Unilateral Retinoblastoma

## Interventions

- **PROCEDURE:** Biospecimen Collection
- **DRUG:** Carboplatin
- **DRUG:** Etoposide
- **PROCEDURE:** Examination Under Anesthesia
- **PROCEDURE:** Magnetic Resonance Imaging
- **DRUG:** Melphalan
- **PROCEDURE:** Ultrasound Biomicroscopy
- **DRUG:** Vincristine

## Key facts

- **NCT ID:** NCT05504291
- **Lead sponsor:** Children's Oncology Group
- **Sponsor class:** NETWORK
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2022-11-04
- **Primary completion:** 2028-03-31
- **Final completion:** 2028-03-31
- **Target enrollment:** 26 (ESTIMATED)
- **Last updated:** 2026-02-17


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05504291

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05504291, "A Study to Give Treatment Inside the Eye to Treat Retinoblastoma". Retrieved via AI Analytics 2026-07-06 from https://api.ai-analytics.org/clinical/NCT05504291. Licensed CC0.

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