# Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS)

> **NCT05508971** · NA · RECRUITING · sponsor: **Oregon Health and Science University** · enrollment: 303 (estimated)

## Conditions studied

- Obstructive Sleep Apnea
- Down Syndrome

## Interventions

- **PROCEDURE:** DISE-Directed Surgery
- **PROCEDURE:** Adenotonsillectomy

## Key facts

- **NCT ID:** NCT05508971
- **Lead sponsor:** Oregon Health and Science University
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-08-02
- **Primary completion:** 2027-12-31
- **Final completion:** 2028-06-30
- **Target enrollment:** 303 (ESTIMATED)
- **Last updated:** 2026-02-10

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05508971

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05508971, "Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS)". Retrieved via AI Analytics 2026-06-14 from https://api.ai-analytics.org/clinical/NCT05508971. Licensed CC0.

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