# A Randomised Controlled Trial, Of N-Acetyl Cysteine (NAC), for Premanifest Huntingtin Gene Expansion Carriers

> **NCT05509153** · PHASE2 · RECRUITING · sponsor: **Western Sydney Local Health District** · enrollment: 160 (estimated)

## Conditions studied

- Huntington Disease

## Interventions

- **DRUG:** NAC
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT05509153
- **Lead sponsor:** Western Sydney Local Health District
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2024-06-01
- **Primary completion:** 2026-11-01
- **Final completion:** 2027-05-01
- **Target enrollment:** 160 (ESTIMATED)
- **Last updated:** 2025-02-28

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05509153

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05509153, "A Randomised Controlled Trial, Of N-Acetyl Cysteine (NAC), for Premanifest Huntingtin Gene Expansion Carriers". Retrieved via AI Analytics 2026-06-24 from https://api.ai-analytics.org/clinical/NCT05509153. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*