Zibotentan and Dapagliflozin Combination, EvAluated in Liver Cirrhosis (ZEAL Study)

PHASE2

Phase

TERMINATED

Status

205

Enrollment

INDUSTRY

Sponsor class

Stopped The study was ended earlier than planned due to a sponsor decision.

Conditions

DRUG: Part A: Placebo (matching zibotentan capsule & matching dapagliflozin tablet)
DRUG: Part A: zibotentan (dose B) + dapagliflozin
DRUG: Part B: Placebo (matching zibotentan capsule & matching dapagliflozin tablet)
DRUG: Part B: placebo (matching zibotentan capsule) + dapagliflozin
DRUG: Part B: zibotentan (dose A) + dapagliflozin
DRUG: Part B: zibotentan (dose B) + dapagliflozin
DRUG: Part B: zibotentan (dose C) + dapagliflozin

AstraZeneca