# Evaluation of the Efficacy of Fomepizole in the Treatment of Acetaminophen Overdose

> **NCT05517668** · PHASE2 · TERMINATED · sponsor: **Richard Dart, MD, PhD** · enrollment: 29 (actual)

## Conditions studied

- Acetaminophen
- Drug Overdose
- Acetaminophen Overdose
- Acetaminophen Poisoning
- Drug-induced Liver Injury
- Liver Failure
- Liver Toxicity

## Interventions

- **DRUG:** Intravenous infusion of N-acetylcysteine
- **DRUG:** Intravenous infusion of Fomepizole (4-MP)

## Key facts

- **NCT ID:** NCT05517668
- **Lead sponsor:** Richard Dart, MD, PhD
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** TERMINATED
- **Start date:** 2022-09-12
- **Primary completion:** 2025-10-31
- **Final completion:** 2025-11-08
- **Target enrollment:** 29 (ACTUAL)
- **Why stopped:** Futility
- **Last updated:** 2025-11-25

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05517668

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05517668, "Evaluation of the Efficacy of Fomepizole in the Treatment of Acetaminophen Overdose". Retrieved via AI Analytics 2026-07-08 from https://api.ai-analytics.org/clinical/NCT05517668. Licensed CC0.

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