# Comparison of Left Bundle Branch Area Versus Right Ventricular Septal Pacing in Patients With High-degree Conduction Disease After Transcatheter Aortic Valve Replacement (Left Bundle BRAVE)

> **NCT05541679** · NA · ACTIVE_NOT_RECRUITING · sponsor: **Main Line Health** · enrollment: 46 (estimated)

## Conditions studied

- Complete Heart Block
- High Degree Second Degree Atrioventricular Block
- Pacemaker-Induced Cardiomyopathy
- Aortic Valve Stenosis

## Interventions

- **DEVICE:** Right ventricular septal pacing followed by left bundle branch area pacing
- **DEVICE:** Left bundle branch area pacing followed by right ventricular septal pacing

## Key facts

- **NCT ID:** NCT05541679
- **Lead sponsor:** Main Line Health
- **Sponsor class:** OTHER
- **Phase:** NA
- **Study type:** INTERVENTIONAL
- **Status:** ACTIVE_NOT_RECRUITING
- **Start date:** 2022-12-28
- **Primary completion:** 2025-12-31
- **Final completion:** 2025-12-31
- **Target enrollment:** 46 (ESTIMATED)
- **Last updated:** 2024-12-10

## Collaborators

- [object Object]
- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05541679

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05541679, "Comparison of Left Bundle Branch Area Versus Right Ventricular Septal Pacing in Patients With High-degree Conduction Disease After Transcatheter Aortic Valve Replacement (Left Bundle BRAVE)". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT05541679. Licensed CC0.

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