# Safety, Ultrasound Conspicuity, and Migration of Twinkling Markers in Patients With Locally Advanced Breast Cancer

> **NCT05547347** · — · SUSPENDED · sponsor: **Mayo Clinic** · enrollment: 15 (estimated)

## Conditions studied

- Anatomic Stage III Breast Cancer AJCC v8
- Locally Advanced Breast Carcinoma
- Resectable Breast Carcinoma

## Interventions

- **PROCEDURE:** Magnetic Resonance Imaging
- **PROCEDURE:** Mammogram
- **PROCEDURE:** Ultrasound
- **PROCEDURE:** Ultrasound-Guided Biopsy
- **DEVICE:** Twinkle marker

## Key facts

- **NCT ID:** NCT05547347
- **Lead sponsor:** Mayo Clinic
- **Sponsor class:** OTHER
- **Phase:** —
- **Study type:** OBSERVATIONAL
- **Status:** SUSPENDED
- **Start date:** 2023-03-21
- **Primary completion:** 2026-12-31
- **Final completion:** 2026-12-31
- **Target enrollment:** 15 (ESTIMATED)
- **Why stopped:** Pending biocompatibility testing
- **Last updated:** 2026-03-31


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05547347

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05547347, "Safety, Ultrasound Conspicuity, and Migration of Twinkling Markers in Patients With Locally Advanced Breast Cancer". Retrieved via AI Analytics 2026-05-29 from https://api.ai-analytics.org/clinical/NCT05547347. Licensed CC0.

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