# Testing the Use of Combination Therapy in Patients With Persistent Low Level Acute Myeloid Leukemia Following Initial Treatment, The ERASE Study (A MyeloMATCH Treatment Trial)

> **NCT05554419** · PHASE2 · NOT_YET_RECRUITING · sponsor: **National Cancer Institute (NCI)** · enrollment: 184 (estimated)

## Conditions studied

- Acute Myeloid Leukemia
- Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome
- Acute Myeloid Leukemia Arising From Previous Myeloproliferative Neoplasm
- Acute Myeloid Leukemia Post Cytotoxic Therapy
- Secondary Acute Myeloid Leukemia

## Interventions

- **DRUG:** Azacitidine
- **PROCEDURE:** Bone Marrow Aspiration and Biopsy
- **DRUG:** Cytarabine
- **PROCEDURE:** Echocardiography Test
- **DRUG:** Liposome-encapsulated Daunorubicin-Cytarabine
- **PROCEDURE:** Multigated Acquisition Scan
- **DRUG:** Venetoclax

## Key facts

- **NCT ID:** NCT05554419
- **Lead sponsor:** National Cancer Institute (NCI)
- **Sponsor class:** NIH
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** NOT_YET_RECRUITING
- **Start date:** 2026-07-01
- **Primary completion:** 2026-08-31
- **Final completion:** 2026-08-31
- **Target enrollment:** 184 (ESTIMATED)
- **Last updated:** 2026-04-13


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05554419

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05554419, "Testing the Use of Combination Therapy in Patients With Persistent Low Level Acute Myeloid Leukemia Following Initial Treatment, The ERASE Study (A MyeloMATCH Treatment Trial)". Retrieved via AI Analytics 2026-06-22 from https://api.ai-analytics.org/clinical/NCT05554419. Licensed CC0.

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