# Head-to-head Comparison of Single Versus Dual Antiplatelet Treatment Strategy After Percutaneous Left Atrial Appendage Closure: a Multicenter, Randomized Study

> **NCT05554822** · PHASE3 · UNKNOWN · sponsor: **Azienda Ospedaliero Universitaria Maggiore della Carita** · enrollment: 574 (estimated)

## Conditions studied

- Left Atrial Appendage Occlusion
- Antiplatelet Therapy

## Interventions

- **DRUG:** Aspirin 100mg
- **DRUG:** Aspirin 100 mg OD plus clopidogrel 75 mg OD

## Key facts

- **NCT ID:** NCT05554822
- **Lead sponsor:** Azienda Ospedaliero Universitaria Maggiore della Carita
- **Sponsor class:** OTHER
- **Phase:** PHASE3
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2021-06-14
- **Primary completion:** 2023-12-31
- **Final completion:** 2023-12-31
- **Target enrollment:** 574 (ESTIMATED)
- **Last updated:** 2022-10-03

## Collaborators

- [object Object]

## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05554822

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05554822, "Head-to-head Comparison of Single Versus Dual Antiplatelet Treatment Strategy After Percutaneous Left Atrial Appendage Closure: a Multicenter, Randomized Study". Retrieved via AI Analytics 2026-06-02 from https://api.ai-analytics.org/clinical/NCT05554822. Licensed CC0.

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