# Effects of Denosumab on Bone Microarchitecture After Total Knee Arthroplasty

> **NCT05559268** · PHASE4 · UNKNOWN · sponsor: **The Affiliated Hospital of Qingdao University** · enrollment: 60 (estimated)

## Conditions studied

- Osteoarthritis, Knee

## Interventions

- **DRUG:** Denosumab 60 MG/ML Injectable Solution [Prolia]
- **DRUG:** Placebo

## Key facts

- **NCT ID:** NCT05559268
- **Lead sponsor:** The Affiliated Hospital of Qingdao University
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2022-10-01
- **Primary completion:** 2023-12-31
- **Final completion:** 2023-12-31
- **Target enrollment:** 60 (ESTIMATED)
- **Last updated:** 2022-09-29


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05559268

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05559268, "Effects of Denosumab on Bone Microarchitecture After Total Knee Arthroplasty". Retrieved via AI Analytics 2026-06-03 from https://api.ai-analytics.org/clinical/NCT05559268. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*