# COMParison of the EffecT of dEvice Closure in Alleviating Migraine With PFO (COMPETE-2)

> **NCT05561660** · PHASE4 · UNKNOWN · sponsor: **Chinese Academy of Medical Sciences, Fuwai Hospital** · enrollment: 460 (estimated)

## Conditions studied

- Migraine
- Patent Foramen Ovale

## Interventions

- **DEVICE:** PFO device closure
- **DRUG:** Aspirin

## Key facts

- **NCT ID:** NCT05561660
- **Lead sponsor:** Chinese Academy of Medical Sciences, Fuwai Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** UNKNOWN
- **Start date:** 2022-10-01
- **Primary completion:** 2024-10-01
- **Final completion:** 2025-10-01
- **Target enrollment:** 460 (ESTIMATED)
- **Last updated:** 2023-01-09


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05561660

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05561660, "COMParison of the EffecT of dEvice Closure in Alleviating Migraine With PFO (COMPETE-2)". Retrieved via AI Analytics 2026-06-25 from https://api.ai-analytics.org/clinical/NCT05561660. Licensed CC0.

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