MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

NCT05564390 · clinicaltrials.gov ↗

PHASE2

Phase

RECRUITING

Status

2000

Enrollment

NIH

Sponsor class

Conditions

Acute Myeloid Leukemia
Acute Myeloid Leukemia Arising From Previous Myelodysplastic/Myeloproliferative Neoplasm
Acute Myeloid Leukemia Post Cytotoxic Therapy
Acute Myeloid Leukemia, Myelodysplasia-Related
Myelodysplastic Syndrome

Interventions

PROCEDURE: Allogeneic Hematopoietic Stem Cell Transplantation
DRUG: Azacitidine
OTHER: Best Practice
PROCEDURE: Biopsy Procedure
PROCEDURE: Biospecimen Collection
PROCEDURE: Bone Marrow Aspiration
PROCEDURE: Bone Marrow Biopsy
DRUG: Busulfan
PROCEDURE: Chest Radiography
PROCEDURE: Computed Tomography
DRUG: Cytarabine
DRUG: Daunorubicin Hydrochloride
DRUG: Decitabine and Cedazuridine
PROCEDURE: Echocardiography Test
BIOLOGICAL: Emavusertib
DRUG: Enasidenib
BIOLOGICAL: Epoetin Alfa
DRUG: Fludarabine
DRUG: Gemtuzumab Ozogamicin
DRUG: Gilteritinib

Sponsor

National Cancer Institute (NCI)