Navitoclax in Relapsed or Refractory High-Risk Myelodysplastic Syndrome

NCT05564650 · clinicaltrials.gov ↗

PHASE1

Phase

ACTIVE_NOT_RECRUITING

Status

6

Enrollment

OTHER

Sponsor class

Conditions

Myelodysplastic Syndrome
Recurrent Myelodysplastic Syndrome
Refractory Myelodysplastic Syndrome

Interventions

BIOLOGICAL: Navitoclax
DRUG: Venetoclax
DRUG: Decitabine
PROCEDURE: Bone Marrow Biopsy
PROCEDURE: Biospecimen Collection
OTHER: Laboratory Biomarker Analysis
OTHER: Quality-of-Life Assessment

Sponsor

Thomas Jefferson University

Collaborators

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