# Relationship Between Abnormal Myocardial Perfusion and Diastolic Dysfunction in Sickle Cell Disease Using PET

> **NCT05583721** · PHASE2 · RECRUITING · sponsor: **St. Jude Children's Research Hospital** · enrollment: 40 (estimated)

## Conditions studied

- Sickle Cell Disease

## Interventions

- **DRUG:** [13N]NH3
- **DRUG:** Lexiscan
- **DIAGNOSTIC_TEST:** Positron emission tomography

## Key facts

- **NCT ID:** NCT05583721
- **Lead sponsor:** St. Jude Children's Research Hospital
- **Sponsor class:** OTHER
- **Phase:** PHASE2
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-10-10
- **Primary completion:** 2027-09
- **Final completion:** 2028-09
- **Target enrollment:** 40 (ESTIMATED)
- **Last updated:** 2026-05-06


## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05583721

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05583721, "Relationship Between Abnormal Myocardial Perfusion and Diastolic Dysfunction in Sickle Cell Disease Using PET". Retrieved via AI Analytics 2026-07-26 from https://api.ai-analytics.org/clinical/NCT05583721. Licensed CC0.

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