# Decolonization to Reduce After-Surgery Events of Surgical Site Infection

> **NCT05586776** · PHASE4 · RECRUITING · sponsor: **University of California, Irvine** · enrollment: 2700 (estimated)

## Conditions studied

- Surgical Site Infection

## Interventions

- **DRUG:** 4% Chlorhexidine Gluconate
- **DRUG:** 2% Mupirocin
- **DRUG:** Soap Without Antiseptic Properties (Placebo)
- **DRUG:** Placebo Nasal Ointment

## Key facts

- **NCT ID:** NCT05586776
- **Lead sponsor:** University of California, Irvine
- **Sponsor class:** OTHER
- **Phase:** PHASE4
- **Study type:** INTERVENTIONAL
- **Status:** RECRUITING
- **Start date:** 2023-01-17
- **Primary completion:** 2027-01
- **Final completion:** 2028-12
- **Target enrollment:** 2700 (ESTIMATED)
- **Last updated:** 2025-07-28

## Collaborators

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## Primary source

ClinicalTrials.gov registry: https://clinicaltrials.gov/study/NCT05586776

## Citation

> US National Library of Medicine, ClinicalTrials.gov registration NCT05586776, "Decolonization to Reduce After-Surgery Events of Surgical Site Infection". Retrieved via AI Analytics 2026-06-08 from https://api.ai-analytics.org/clinical/NCT05586776. Licensed CC0.

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*[Clinical trials dataset](/datasets/clinical-trials) · CC0 1.0*